Symantec does not recommend installing Backup Exec on the same disk that the cluster quorum is installed on. If you have to specify a new drive letter for the quorum disk during a recovery process, Backup Exec will not recognize the new drive and will not run.
See Specifying a new drive letter for the cluster quorum disk.
The Remote Agent is automatically installed on all the nodes in the cluster. If this installation of Backup Exec will be used to back up remote servers outside the cluster, install the Remote Agent on those remote servers as well.
To install Backup Exec on a Microsoft Cluster Server
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Install Backup Exec on all the nodes that you want in the cluster. Use the same installation path for each node.
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From the node that you want to be the active node, start Backup Exec.
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From the Tools menu, point to Wizards, and then click Cluster Configuration Wizard.
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Follow the instructions on the screen.
On the Virtual Server Information screen, Backup Exec automatically displays a default name called BKUPEXECVRS for the virtual server. Type a new default name if you do not want to use the default.
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When the Cluster Configuration Wizard completes, create a device pool that contains all the locally attached storage devices on each node to be used when failover occurs. This ensures that jobs can be run on the storage devices that are attached to the failover nodes.
More Information
Enabling or disabling checkpoint restart
Configurations for Backup Exec and Microsoft Cluster Servers