You can create a backup-to-disk folder in any of the following locations to which you can write a file:
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NTFS partitions (local or remote)
The backup-to-disk folder must exist on an NTFS partition for backup jobs in which the Granular Recovery Technology (GRT) option is selected. This option is available for Microsoft Exchange databases and storage groups, Microsoft Active Directory, and Microsoft SharePoint content database and Team database.
See Recommendations for using backup-to-disk folders with backup jobs that use Granular Recovery Technology.
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Network Attached Storage (NAS) devices
If a NAS device is emulating a Windows operating system, contact the NAS manufacturer for assistance before creating backup-to-disk folders on the NAS device. Symantec does not certify NAS devices. If the operating system is a proprietary operating system and not a true Windows operating system, Symantec cannot properly troubleshoot the device.
You should create a backup-to-disk folder on a different physical disk than the disk you want to back up. For example, if the Backup Exec Advanced Open File Option (AOFO) is used to snap volumes during a backup, and if the destination device is a backup-to-disk folder, the backup-to-disk folder should be on a separate volume that is not being snapped.
Similarly, when making selections for backups that you are targeting to a backup-to-disk folder, avoid including that folder in the selections for the job. For example, if you create a new backup-to-disk folder in C:\Backup Folders and then select the entire C:\ volume for backup, make sure that you exclude C:\Backup Folders from the selection list.
More Information
Requirements for creating a removable backup-to-disk folder
Creating a backup-to-disk folder by using the Backup-to-Disk Wizard