You can designate a default preferred server configuration for all of your backup jobs that contain the appropriate replication data. When you back up data from a Microsoft Exchange Database Availability Group, you can set up Backup Exec to use your default preferred server configuration. You can override the default preferred server configuration for specific jobs in the backup job or selection list properties.
See About preferred server configurations.
See Creating a backup job by setting job properties.
If you no longer want the preferred server configuration to be the default, you can remove its default status.
See Removing the default status for a preferred server configuration.